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LNP023 hydrochloride
CAS No. 1646321-63-2
LNP023 hydrochloride ( Iptacopan HCl )
产品货号. M23738 CAS No. 1646321-63-2
LNP023 hydrochloride is an orally bioavailable, highly potent and highly selective factor B inhibitor with an IC50 of 10 nM.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥2657 | 有现货 |
|
| 10MG | ￥4560 | 有现货 |
|
| 25MG | ￥7120 | 有现货 |
|
| 50MG | ￥9639 | 有现货 |
|
| 100MG | ￥13122 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称LNP023 hydrochloride
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述LNP023 hydrochloride is an orally bioavailable, highly potent and highly selective factor B inhibitor with an IC50 of 10 nM.
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产品描述LNP023 hydrochloride is an orally bioavailable, highly potent and highly selective factor B inhibitor with an IC50 of 10 nM. LNP023 shows direct, reversible, and high-affinity binding to human factor B with a KD of 7.9 nM.
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同义词Iptacopan HCl
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通路Others
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靶点Other Targets
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受体factor B
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研究领域——
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适应症——
化学信息
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CAS Number1646321-63-2
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分子量459.0
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分子式C25H31ClN2O4
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纯度>98% (HPLC)
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溶解度DMSO:250 mg/mL (544.69 mM; Need ultrasonic);H2O:50 mg/mL (108.94 mM; ultrasonic and warming)
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SMILESO=C(O)C1=CC=C([C@H]2N(CC3=C(OC)C=C(C)C4=C3C=CN4)CC[C@H](OCC)C2)C=C1.[H]Cl
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Dimitrios C Mastellos, et al. Expanding Complement Therapeutics for the Treatment of Paroxysmal Nocturnal Hemoglobinuria. Semin Hematol. 2018 Jul;55(3):167-175.
产品手册
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